Relative levels of protection of RiVax peptides by PB10, R70, and WECB2, as defined by HX-MS. RiVax was subjected to HX-MS analysis in the presence of (A) PB10, (B) R70, and (C) WECB2. The ΔHX values for each RiVax peptide are shown and colored according to their k-means categorization as follows: strong protection, deep blue; intermediate protection, light blue; insignificant protection, gray; deprotection, yellow.