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. 2017 Dec 5;7:16956. doi: 10.1038/s41598-017-17034-5

Table 3.

PD-L1 IHC scoring according to the SP142-IHC assay scoring algorithm.

SP142-IHC assay Total Kappa value P value McNemar-Bowker
0 1+ 2+ 3+
22C3-IHC assay 0 40 5 0 0 45 0.481P < 0.001 P < 0.001
1+ 21 15 0 0 36
2+ 9 11 5 1 26
3+ 4 6 9 9 28
Total 74 37 14 10 135

0 indicates negative, 1+ weakly positive, 2+ moderately positive, and 3+ strongly positive PD-L1 expression.