TABLE 2 .
HMO profiles in milk collected at postnatal day 21
| HMOa | Mean (SD) HMO concn (mg/ml) |
Corrected P valueb |
|
|---|---|---|---|
| CON (n = 32) | EVC001-fed (n = 34) | ||
| Total | 14.37 (2.80) | 13.81 (0.43) | NS |
| 2′-FL | 1.62 (0.97) | 1.71 (1.04) | NS |
| 3′-FL | 0.5 (0.33) | 0.55 (0.05) | NS |
| 3000 | 0.18 (0.17) | 0.18 (0.06) | NS |
| LDFT | 0.11 (0.02) | 0.15 (0.03) | NS |
| LNT, LNnT | 3.35 (0.31) | 2.89 (0.24) | NS |
| LNFP I | 2.05 (0.31) | 1.85 (0.27) | NS |
| LNFP II, III, V | 1.12 (0.13) | 1.09 (0.12) | NS |
| 3′-SLN, 6′-SLN | 0.01 (0) | 0.01 (0) | NS |
| LNH, LNnH | 0.47 (0.05) | 0.4 (0.03) | NS |
| LNDFH I, II | 0.21 (0.03) | 0.23 (0.02) | NS |
| 3′-SL, 6′-SL | 1.54 (0.07) | 1.62 (0.07) | NS |
| MFLNH, IFLNH | 0.78 (0.04) | 0.77 (0.04) | NS |
| 4300 | 0.05 (0) | 0.04 (0) | NS |
| 4220 | 0.31 (0.02) | 0.31 (0.01) | NS |
| 5310 | 0.18 (0.01) | 0.15 (0.01) | NS |
| LSTa, b, c | 0.31 (0.02) | 0.31 (0.02) | NS |
| 4230 | 0.08 (0.01) | 0.09 (0.01) | NS |
| 5320 | 0.2 (0.01) | 0.18 (0.01) | NS |
| 6410 | 0.14 (0.01) | 0.14 (0.01) | NS |
| 3111 | 0.01 (0) | 0.01 (0) | NS |
| 5330 | 0.12 (0.01) | 0.11 (0) | NS |
| 4201 | 0.32 (0.03) | 0.3 (0.03) | NS |
| 6420 | 0.11 (0.01) | 0.1 (0.01) | NS |
| 5340 | 0.02 (0) | 0.02 (0) | NS |
| 4211 | 0.47 (0.03) | 0.47 (0.02) | NS |
| 6440 | 0.02 (0) | 0.02 (0) | NS |
| 5301 | 0.01 (0) | 0.01 (0) | NS |
| 5311 | 0.04 (0) | 0.04 (0) | NS |
| 6401 | 0.02 (0) | 0.02 (0) | NS |
| 5321 | 0.02 (0) | 0.02 (0) | NS |
| 6430 | 0.02 (0) | 0.02 (0) | NS |
| 4221 | 0.01 (0) | 0.01 (0) | NS |
| 5331 | 0 (0) | 0 (0) | NS |
a
Abbreviations: 2′-FL, 2′-fucosyllactose; 3′-FL, 3′-fucosyllactose; LDFT, lacto-difucosyltetraose; LNT, lacto-N-tetraose; LNnT, lacto-N-neotetraose; LNFP, lacto-N-fucosyllpentose; SLN, sialyllactosamine; LNH, lacto-N-hexose; LNnH, lacto-N-neohexose; DFLNH, difucosyllacto-N-hexose; MFLNH, mono-fucosyllacto-N-hexose; IFLNH, isomeric fucoysllactosyl-N-hexose; LST, sialyl-lacto-N-tetraose; LSTa, b, c, isomers of LST. Structural formula for unnamed structures is hexose | hexose-N-acetylglucosamine/galactosamine | fucose | sialic acid.
b
P values were determined with a multiple t test and the Holm-Sidak correction. NS, not significant.