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. 2017 Nov 22;7(11):170204. doi: 10.1098/rsob.170204

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© 2017 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 4. — Substrate recognition is mediated by coactivators and Apc10. (a) D-box receptor on Cdh1, (b) D-box co-receptor (Cdh1 and Apc10), (c) KEN-box receptor on Cdh1, (d) ABBA-motif interactions with Cdh1. Coordinates in (a,c,d) are based on the S. cerevisiae Cdh1–Acm1 complex (PDB: 4BH6) [71]. (b) Based on APC/C^Cdh1.Emi1 complex (PDB 4UI9) [80].