Figure 2.

Overview of extracellular vesicle release and uptake. Schematic illustrating the generation of exosomes (blue) from endosomal compartments and plasma membrane–derived microvesicles (pink) from a donor cell. Major mechanisms of uptake by a recipient cell are indicated. The major molecular cargo of exosomes is also illustrated in the cutout, and an apoptotic cell shown to demonstrate the generation of apoptotic bodies.