Table 1. Univariate analysis of baseline characteristics among patients with and without IBD who underwent CRC surgery: National Inpatient Sample 2008–2012.
| Non-IBD CRC ( n =394,605) | IBD CRC ( n =3,242) | P value | UC ( n =1,902) | P value | CD ( n =1,340) | P value | |
|---|---|---|---|---|---|---|---|
| Age (mean, CI) | 67.82 (67.64, 68.01) | 61.33 (60.17, 62.48) | <0.0001 | 61.62 (60.14, 63.10) | <0.0001 | 60.91 (59.13, 62.70) | <0.0001 |
| Sex | 0.0751 | 0.0048 | 0.5576 | ||||
| Male | 197,489 (50.05%) | 1,731 (53.39%) | 1,085 (57.02%) | 646 (48.22%) | |||
| Female | 197,116 (49.95%) | 1,511 (46.61%) | 817 (42.98%) | 694 (51.78%) | |||
| Race | <0.0001 | 0.0058 | 0.0001 | ||||
| White | 304,569 (77.18%) | 2,790 (86.06%) | 1,607 (84.47%) | 1,183 (88.33%) | |||
| Black | 40,805 (10.34%) | 187 (5.77%) | 109 (5.74%) | 78 (5.81%) | |||
| Hispanic | 26,179 (6.63%) | 140 (4.31%) | 99 (5.21%) | 41 (3.04%) | |||
| Other | 23,052 (5.84%) | 125 (3.85%) | 87 (4.58%) | 38 (2.82%) | |||
| Insurance | <0.0001 | <0.0001 | <0.0001 | ||||
| Medicare | 226,264 (57.34%) | 1,309 (40.38%) | 764 (40.18%) | 545 (40.65%) | |||
| Medicaid | 20,484 (5.19%) | 192 (5.91%) | 123 (6.46%) | 69 (5.13%) | |||
| Private | 128,021 (32.44%) | 1,597 (49.28%) | 923 (48.54%) | 674 (50.33%) | |||
| Other | 19,836 (5.03%) | 144 (4.44%) | 92 (4.83%) | 52 (3.88%) | |||
| Income quartile a | <0.0001 | 0.0002 | <0.0001 | ||||
| 1 | 100,612 (25.50%) | 550 (16.96%) | 340 (17.87%) | 210 (15.66%) | |||
| 2 | 100,372 (25.44%) | 730 (22.51%) | 433 (22.75%) | 297 (22.16%) | |||
| 3 | 97,319 (24.66%) | 919 (28.34%) | 536 (28.20%) | 382 (28.53%) | |||
| 4 | 96,302 (24.40%) | 1,044 (32.20%) | 593 (31.18%) | 451 (33.64%) | |||
| Elixhauser comorbidity | 0.0015 | 0.0233 | 0.0310 | ||||
| <3 | 212,795 (53.93%) | 1,949 (60.13%) | 1,137 (59.77%) | 812 (60.65%) | |||
| ≥3 | 181,810 (46.07%) | 1,292 (39.87%) | 765 (40.23%) | 527 (39.35%) | |||
| Hospital bed size b | 0.0011 | 0.0082 | 0.0712 | ||||
| Small | 44,345 (11.24%) | 305 (9.40%) | 178 (9.35%) | 127 (9.47%) | |||
| Medium | 95,707 (24.25%) | 607 (18.73%) | 351 (18.43%) | 256 (19.14%) | |||
| Large | 254,553 (64.51%) | 2,330 (71.88%) | 1,374 (72.22%) | 956 (71.39%) | |||
| Hospital type | <0.0001 | <0.001 | 0.0213 | ||||
| Rural | 40,699 (10.31%) | 158 (4.86%) | 85 (4.48%) | 72 (5.40%) | |||
| Urban non-teaching | 166,988 (42.32%) | 1,217 (37.54%) | 650 (34.18%) | 567 (42.30%) | |||
| Urban teaching | 186,918 (47.37%) | 1,867 (57.60%) | 1,167 (61.34%) | 701 (52.30%) | |||
| Hospital region | 0.0033 | 0.0068 | 0.2265 | ||||
| Northeast | 87,938 (22.29%) | 850 (26.23%) | 505 (26.56%) | 345 (25.77%) | |||
| Midwest | 73,744 (18.69%) | 670 (20.66%) | 386 (20.31%) | 283 (21.16%) | |||
| South | 161,975 (41.05%) | 1,087 (33.54%) | 614 (32.30%) | 473 (35.29%) | |||
| West | 70,948 (17.98%) | 634 (19.57%) | 396 (20.83%) | 238 (17.79%) | |||
| Lymph node positivity | 0.0359 | 0.0373 | 0.4166 | ||||
| No | 313,145 (79.36%) | 2,680 (82.68%) | 1,589 (83.55%) | 1,091 (81.44%) | |||
| Yes | 81,460 (20.64%) | 561 (17.32%) | 313 (16.45%) | 249 (18.56%) | |||
| Distant metastasis | 0.0121 | 0.0287 | 0.2342 | ||||
| No | 337,748 (85.59%) | 2,880 (88.85%) | 1,702 (89.47%) | 1,178 (87.97%) | |||
| Yes | 56,857 (14.41%) | 362 (11.15%) | 200 (10.53%) | 161 (12.03%) |
Abbreviations: CD, Crohn’s disease; CI, confidence interval; CRC, colorectal cancer; IBD, inflammatory bowel disease; UC, ulcerative colitis.
a
Income quartile 1 contains lowest earning households. The exact income ranges vary from year to year.
b
Hospital bed size is classified by number of beds, and also by hospital region and type. For example, a large hospital requires more than 450 beds if it is an urban teaching hospital in the Southern region, while a large rural hospital in the Southern region only requires 75 beds. For additional information, please see www.hcup-us.ahrq.gov/db/vars/hosp_bedsize/nisnote.jsp.