Table 2. Multivariate analysis of CRC location, surgical approach, and surgery location among patients with and without IBD: National Inpatient Sample 2008–2012.
| Non-IBD ( n =394,605) | IBD ( n =3,242) | Adjusted P value | UC ( n =1,902) | Adjusted P value | CD ( n =1,340) | Adjusted P value | |
|---|---|---|---|---|---|---|---|
| Cancer location | 0.0006a | 0.0046a | 0.0004a | ||||
| Right colon | 185,999 (47.14%) | 1,311 (40.44%) | 676 (35.53%) | 635 (47.41%) | |||
| Left colon | 92,374 (23.41%) | 649 (20.01%) | 473 (24.87%) | 175 (13.10%) | |||
| Non-specified colon | 22,523 (5.71%) | 263 (8.12%) | 165 (8.67%) | 98 (7.34%) | |||
| Rectal | 93,708 (23.75%) | 1,019 (31.44%) | 588 (30.94%) | 431 (32.15%) | |||
| Surgery type | 0.0003b | 0.0009b | 0.0839b | ||||
| Laparoscopic | 99,454 (25.20%) | 659 (20.33%) | 365 (19.18%) | 294 (21.95%) | |||
| Open | 295,151 (74.80%) | 2,583 (79.67%) | 1,537 (80.82%) | 1,046 (78.05%) | |||
| Surgery location c | <0.0001a | <0.0001a | <0.0001a | ||||
| Total colectomy | 5,510 (1.40%) | 1,120 (34.54%) | 882 (46.36%) | 238 (17.76%) | |||
| Proctectomy | 95,311 (24.15%) | 638 (19.69%) | 307 (16.13%) | 332 (24.75%) | |||
| Partial colectomy | 293,783 (74.45%) | 1,483 (45.76%) | 713 (37.51%) | 770 (57.49%) |
Abbreviations: CD, Crohn’s disease; CRC, colorectal cancer; IBD, inflammatory bowel disease; UC, ulcerative colitis.
a
Multivariate analysis adjusts for age; gender; race; insurance; income; Elixhauser score; hospital size, type, and region; lymph node positivity; and distant metastasis.
b
Multivariate analysis adjusts for age; gender; race; insurance; income; Elixhauser score; hospital size, type, and region; cancer location; lymph node positivity; and distant metastasis.
c
Patients were classified according to most complex surgery received. Some patients with total colectomy may have also undergone proctectomy.