Table 3. Multivariate analysis of health-care resource utilization and CRC surgical outcomes among patients with and without IBD: National Inpatient Sample 2008–2012a.
| Non-IBD ( n =394,605) | IBD ( n =3,242) | AC/AOR (95% CI) | UC ( n =1,902) | AC/AOR (95% CI) | CD ( n =1,340) | AC/AOR (95% CI) | |
|---|---|---|---|---|---|---|---|
| LOS (days)b | 8.66 (8.59, 8.74) | 9.90 (9.32, 10.47) | 0.86 (0.42, 1.30) | 9.71 (9.02, 10.41) | 0.38 (−0.16, 0.91) | 10.16 (9.18, 11.14) | 1.44 (0.69, 2.18) |
| Total hospital charge (US$)c | 72,038 (70,454, 73,621) | 87,619 (80,241, 94,998) | 1,929 (−2,472, 6,329) | 88,035 (78,450, 97,620) | 2,232 (−4,545, 9,008) | 87, 029 (76,036, 98,023) | 1,433 (−3,351, 6,216) |
| Blood transfusionb | 84,413 (21.39%) | 854 (26.34%) | 1.59 (1.30, 1.94) | 512 (26.90%) | 1.66 (1.29, 2.13) | 342 (25.54%) | 1.49 (1.10, 2.02) |
| All postsurgical complicationsd | 115,414 (29.25%) | 1,090 (33.63%) | 1.26 (1.06, 1.50) | 608 (31.99%) | 1.10 (0.88, 1.38) | 482 (35.96%) | 1.51 (1.17, 1.95) |
| Postoperative infectiond | 15,480 (3.92%) | 256 (7.90%) | 1.69 (1.20, 2.38) | 131 (6.89%) | 1.58 (1.04, 2.42) | 125 (9.33%) | 2.50 (1.65, 3.78) |
| Deep vein thrombosisd | 3,319 (0.84%) | 68 (2.09%) | 2.42 (1.36, 4.28) | 40 (2.11%) | 2.57 (1.19, 5.55) | 28 (2.05%) | 2.79 (1.25, 6.25) |
| Respiratoryd | 8,859 (2.25%) | 36 (1.11%) | 0.46 (0.22, 0.95) | 10 (0.49%) | 0.22 (0.06, 0.89) | 27 (1.99%) | 1.01 (0.45, 2.30) |
| Included central nervous systemd | 647 (0.16%) | ≤10 (0.29%) | 1.00 (0.22, 4.52) | ≤10 (0.49%) | 1.73 (0.36, 8.28) | 0 (0.00%) | — |
| Cardiacc | 8,641 (2.19%) | 52 (1.61%) | 0.66 (0.34, 1.25) | 33 (1.73% | 0.76 (0.35, 1.66) | 19 (1.45%) | 0.75 (0.27, 2.06) |
| Peripheral vasculard | 934 (0.24%) | ≤10 (0.15%) | 0.57 (0.07, 4.52) | ≤10 (0.26%) | 1.13 (0.13, 9.70) | 0 (0.00%) | — |
| Gastrointestinald | 36,531 (9.26%) | 299 (9.22%) | 0.81 (0.60, 1.11) | 165 (8.66%) | 0.93 (0.65, 1.32) | 134 (10.03%) | 1.17 (0.78, 1.76) |
| Genitourinaryd | 5,483 (1.39%) | 32 (0.98%) | 0.57 (0.25, 1.28) | 13 (0.71%) | 0.46 (0.14, 1.50) | 18 (1.36%) | 0.99 (0.36, 2.73) |
| Hemorrhage, hematoma, or seromad | 16,338 (4.14%) | 205 (6.33%) | 1.14 (0.80, 1.63) | 105 (5.52% | 1.10 (0.69, 1.75) | 100 (7.48%) | 1.81 (1.15, 2.85) |
| Wound dehiscence, rupture, non-healing, or disruptiond | 5,139 (1.30%) | 73 (2.25%) | 1.40 (0.81, 2.41) | 29 (1.54%) | 1.01 (0.45, 2.26) | 44 (3.26%) | 2.73 (1.37, 5.43) |
| Pulmonary embolismd | 3,587 (0.91%) | 30 (0.94%) | 0.93 (0.39, 2.18) | 26 (1.36%) | 1.47 (0.57, 3.77) | ≤10 (0.33%) | 0.40 (0.06, 2.87) |
| Postoperative anemiad | 48,215 (12.22%) | 465 (14.33%) | 1.16 (0.86, 1.56) | 269 (14.15%) | 1.23 (0.91, 1.65) | 196 (14.60%) | 1.38 (0.94, 2.02) |
| Mortalityb | 8,118 (2.06%) | 54 (1.66%) | 0.93 (0.50, 1.72) | 32 (1.69%) | 0.88 (0.40, 1.98) | 22 (1.66%) | 0.96 (0.38, 2.43) |
Abbreviations: AC, adjusted coefficients; AOR, adjusted odds ratios; CD, Crohn’s disease; CI, confidence interval; CRC, colorectal cancer; IBD, inflammatory bowel disease; LOS, length of stay; UC, ulcerative colitis.
AC and AOR are compared to patients without IBD.
Multivariate analysis adjusts for age; gender; race; insurance; income; Elixhauser score; hospital size, type, and region; postoperative complications; cancer location; lymph node positivity; distant metastasis; and surgery type and location.
Multivariate analysis adjusts for age; gender; race; insurance; income; Elixhauser score; hospital size, type, and region; postoperative complications; cancer location; lymph node positivity; distant metastasis; LOS; and surgery type and location.
Multivariate analysis adjusts for age; gender; race; insurance; income; Elixhauser score; hospital size, type, and region; cancer location; surgery type and location; lymph node positivity; and distant metastasis.