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Graphic representation of how SNPS and stress regulate FKBP5 expression through ageing. Along with ageing, common variants of the FKBP5 gene are known to increase expression of FKBP5. These SNPs and their interaction with environmental factors (ex. stress event) are associated with augmented FKBP5 expression leading to a higher risk of developing psychiatric disorders. (Online version in colour.)
