Table 3.
Disease association overlap.
| A. | |||||
|---|---|---|---|---|---|
| Disease 1 | Disease 2 | Hypergeometric p-value | |||
| DM | JDM | 3.54E-12 | |||
| DMD | JDM | 2.08E-02 | |||
| DMD | LGMD2A | 9.09E-03 | |||
| BMD | LGMD2I | 5.38E-03 | |||
| MELAS | PEO | 6.95E-04 | |||
| IBM | PM | 7.26E-10 | |||
| B. | |||||
| Correlations based on DGA scores | |||||
| Significant | Not significant | Total | |||
| Correlations based on known disease genes | Significant | 6 | 20 | 26 | |
| Not Significant | 14 | 150 | 164 | ||
| Total | 20 | 170 | 190 | ||
A. This table provides associations that overlap between associations calculated based on the DGA scores and associations that share a genetic basis (disease-gene list based). Hypergeometric p-values of the overlap are also presented. B. Contingency table to evaluate the hypothesis that significant disease associations also significantly shared disease genes.