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Dapoxyl does not affect the kinetics and mechanism of insulin aggregation. (a) Aggregation kinetic traces showing that the formation of mature fibrils is not perturbed by the presence of dapoxyl. Curves with and without dapoxyl are shown for two representative concentrations: 44 and 174 μM. (b) Half-times for the aggregation reactions (t1/2) are highly similar with and without dapoxyl. The data are plotted on a log–log scale.
