Table 3.
Distribution of NAT2 genotype among the healthy Jordanian population (n = 68).
| NAT2 allele | Wild genotype: frequency (proportion, 95% CI) | Heterozygote genotype: frequency (proportion, 95% CI) | Homozygote genotype: frequency (proportion, 95% CI) |
|---|---|---|---|
| NAT2*14 (191G>A) | G/G: 0 | G/A: 0.014 (0.007–0.025) | A/A: 0 |
| NAT2*13 (282C>T) | C/C: 44 (0.647, 0.533–0.761) | C/T: 16 (0.235, 0.134–0.336) | T/T: 8 (0.11, 0.041–0.194) |
| NAT2*5 (341T>C) | T/T: 20 (0.294, 0.186–0.402) | T/C: 30 (0.44, 0.323–0.559) | C/C:18 (0.264, 0.160–0.370) |
| NAT2*11 (481C>T) | C/C: 28 (0.411, 0.295–0.529) | C/T: 32 (0.471, 0.352–0.589) | T/T: 8 (0.11, 0.41–0.194) |
| NAT2*6 (590G>A) | G/G: 34 (0.500, 0.381–0.619) | G/A: 26 (0.382, 0.267–0.498) | A/A: 8 (0.11, 0.41–0.194) |
| NAT2*12 (803A>G) | A/A: 36 (0.529, 0.411–0.648) | A/G: 20 (0.294, 0.186–0.402) | G/G: 12 (0.176, 0.086–0.267) |
CI: Confidence interval.