Figure 7.

Schematic presentation of possible molecular dialogues between transgenic lines carrying RNAi constructs and colonizing Pst. Fungal dsRNA, produced inside transgenic wheat cells, is cleaved by the plant silencing machinery using endonuclease-type DICER enzymes into small silencing molecules (siRNAs). These siRNAs are trapped by a complex of proteins, and transported to the paramural space. After passing the haustorial cell wall, the silencing molecules trigger RNAi of their mRNA targets, and may act as primers leading to the activation of systemic silencing signals, thus inducing the immunity system of transgenic wheat by mechanisms including ETI and PTI.