Table 1.
ED50 values and 95% confidence intervals of stimulus substitution test drugs in groups of rats trained to discriminate 1.0 or 3.0 mg/kg 4-MMC (IP) from saline
Test Compound | ED50 (mg/kg) (95% CI) in 1.0 mg/kg 4-MMC group |
ED50 (mg/kg) (95% CI) in 3.0 mg/kg 4-MMC group |
---|---|---|
| ||
4-MMC | 0.18 (0.08–0.38) | 0.50 (0.27–0.96) |
MDPV | 0.63 (0.17–1.08) | ------ |
d-Amphetamine | 0.48 (0.16–0.79) | ------ |
(+)-Methamphetamine | ------ | ------ |
Cocaine | 0.92 (0.20–1.64) | ------ |
MDMA | 0.16 (0.07–0.36) | 1.77 (1.00–3.17)* |
(+)-LSD | ------ | ------ |
(+)-Fenfluramine | ------ | 1.96 (0.40–3.52) |
indicates a statistically significant difference between training groups