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. 2017 Dec 5;17:279. doi: 10.1186/s12877-017-0672-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Cardiovascular outcomes and all-cause mortality for SBP 130 to <140 versus ≥ 140 mmHg. Panel a: stroke; Panel b: acute myocardial infarction; Panel c: cardiovascular mortality; Panel d: All-cause mortality. Results are stratified by study design. The size of the marker represents the weight of each trial. Weighted average of blood pressure is described for each outcome. SBP, systolic blood pressure; RR, relative risk; 95% CI, 95% confidence interval; RCTs, randomized controlled trials; D + L, DerSimonian-Laird random effect model