Table 3.
GO and KEGG pathway analysis of 44 gene
| Data source | Feature ID | Name | Genes | P Value |
|---|---|---|---|---|
| GO Molecular Function | GO:0031995 | insulin-like growth factor II binding | IGFBP1, IGFBP6 | 1.25E-04 |
| GO Molecular Function | GO:0031994 | insulin-like growth factor I binding | IGFBP1, IGFBP6 | 1.60E-04 |
| GO Molecular Function | GO:0005539 | glycosaminoglycan binding | SERPINA5, VCAN | 1.00E-03 |
| GO Molecular Function | GO:0016597 | amino acid binding | ASS1, PAH | 1.00E-03 |
| GO Biological Process | GO:0007588 | excretion | AQP6, ATP6V0A4, SLC12A1, UMOD | 1.76E-06 |
| GO Biological Process | GO:0071242 | cellular response to ammonium ion | ASS1, SLC18A2 | 4.50E-06 |
| GO Biological Process | GO:0048878 | chemical homeostasis | SLC12A1, UMOD | 1.35E-05 |
| GO Biological Process | GO:0051412 | response to corticosterone | FOSB, MAOB, SLC18A2 | 1.38E-05 |
| GO Cellular Component | GO:0005615 | extracellular space | ANGPTL4, DEFB1, FLRT3, HILPDA, IGFBP1, IGFBP6, LCN2, MMP7, SERPINA5, SFTPB, TACSTD2, UMOD, VCAN | 8.42E-07 |
| GO Cellular Component | GO:0016324 | apical plasma membrane | AQP6, ATP6V0A4, MAL, RHCG, SLC12A1, UMOD | 2.02E-05 |
| GO Cellular Component | GO:0005576 | extracellular region | ANGPTL4, C7, DEFB1, IGFBP1, IGFBP6, LCN2, MMP7, PLIN2, SERPINA5, TFPI2, UMOD, VCAN | 3.77E-05 |
| GO Cellular Component | GO:0005578 | proteinaceous extracellular matrix | ANGPTL4, FLRT3, MMP7, TFPI2, VCAN | 1.43E-04 |
| Cancer Gene Index [CGI] | C4863 | prostate cancer | AKR1C2, ANGPTL4, ASS1, GSTA1, IGFBP1, IGFBP6, LCN2, MAL, MT1G, S100A2, TFPI2, VCAN | 3.20E-06 |
| DISEASE DB (Univ of Copenhagen) | DOID:6245 | Renal oncocytoma | AQP6, CLDN8, KRT7 | 6.14E-06 |
| Cancer Gene Index [CGI] | C9385 | renal-cell cancer | ASS1, DEFB1, IGFBP6, LCN2, SERPINA5, UMOD, VCAN | 1.41E-05 |
| Cancer Gene Index [CGI] | C2978 | cysts | GSTA1, IGFBP1, IGFBP6, LCN2, MAL, UMOD | 1.45E-05 |
| KEGG | path:hsa05030 | Cocaine addiction | FOSB, MAOB, SLC18A2 | 1.68E-04 |
| REACTOME | REACT_15518 | Transmembrane transport of small molecules | ABCA8, AQP6, ATP6V0A4, LCN2, RHCG, SLC12A1, SLC18A2 | 2.28E-04 |
| KEGG | path:hsa05031 | Amphetamine addiction | FOSB, MAOB, SLC18A2 | 4.19E-04 |
| KEGG | path:hsa01230 | Biosynthesis of amino acids | ALDOB, ASS1, PAH | 1.00E-03 |
| KEGG | path:hsa00360 | Phenylalanine metabolism | MAOB, PAH | 1.00E-03 |