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. 2017 Dec 5;130(23):2829–2835. doi: 10.4103/0366-6999.219143

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Copyright: © 2017 Chinese Medical Journal

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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SA injection promoted the expressions of the neurotrophic factor such as GDNF in the diabetic mice (n = 24 per group). Three and six days post wound, GDNF mRNA and protein expression in control group, diabetic group, diabetic + SA group, and diabetic + SA + VEGFR1-BL group were detected (*P < 0.05). GDNF: Glial cell line-derived neurotrophic factor; SA: Safflower extract and aceglutamide; qPCR: Quantitative polymerase chain reaction; VEGFR1-BL: Vascular endothelial growth factor receptor 1-blocking antibody.