Table 1.
Predictors of Postsurgical Recurrence
| Study | Type of Study | Type of Recurrence | Significant Predictor | Outcome |
|---|---|---|---|---|
| Cottone et al22 | Retrospective | Clinical | Tobacco smoke | HR, 1.46 (95% CI, 1.1-1.8) |
| Poggioli et al60 | Prospective, observational | Surgical | Disease duration <6 years | P=.009 |
| Bernell et al15 | Retrospective | Clinical | Perianal disease | RR, 1.6 (95% CI, 1.2-2.3) |
| McLeod et al19 | Retrospective | Endoscopic | Prior resection | OR, 1.78 (95% CI, 1.06-2.90) |
| Clinical | Prior resection | OR, 2.00 (95% CI, 1.14-3.60) | ||
| Sokol et al24 | Retrospective | Clinical | Tobacco smoke | HR, 1.94 (95% CI, 1.06-3.60) |
| Clinical | Submucosal plexitis | HR, 1.87 (95% CI, 1.00-3.46) | ||
| Simillis et al18 | Meta-analysis | Surgical | Granuloma | HR, 1.62 (95% CI, 1.19-2.21) |
| Fortinsky et al61 | Retrospective | Endoscopic | Penetrating disease | HR, 1.50 (95% CI, 1.00-2.10) |
| Clinical | Tobacco smoke | HR, 2.25 (95% CI, 1.27-4.01) | ||
| Clinical | Upper GI involvement | HR, 4.00 (95% CI, 1.82-8.33) |
GI, gastrointestinal; HR, hazard ratio; OR, odds ratio; RR, relative risk.