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. 2017 Dec 5;17:820. doi: 10.1186/s12885-017-3809-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Survival outcomes in relation to p-IGF1R, IGF1R and/or SphK1 protein expression in breast cancer patients. Kaplan-Meier analysis was performed to measure the overall survival (OS) following stratification for high vs. low p-IGF1R, IGF1R and SphK1 protein expression as follows: a. IGF1R; b. p-IGF1R; c. IGF1R and SphK1 co-expression and d. p-IGF1R and SphK1 co-expression as described under Methods