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Survival outcomes in relation to p-IGF1R, IGF1R and/or SphK1 protein expression in ER positive and negative breast cancer tissues. Kaplan-Meier analysis was performed to measure the overall survival (OS) following stratification for high vs. low IGF1R, SphK1 protein expression stratified for ER expression as follows: a. IGF1R (ER-positive); b. IGF1R and SphK1 co-expression (ER-positive); C. IGF1R (ER-negative) and D. IGF1R and SphK1 (ER-negative) as described under Methods
