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Chou Talalay Drug Synergism (Combination Index)
| MCF7 (ER+) | CI (mean ± SD) |
| 4 μM SKI-II + 0.4 μM OSI-906 – MTT Assay | 0.49 ± 0.40 (n = 3) |
| 4 μM SKI-II + 0.4 μM OSI-906 – Clonogenic Assay | 0.38 ± 0.28 (n = 6) |
| T47D (ER+) | CI (mean ± SD) |
| 4 μM SKI-II + 0.4 μM OSI-906 – Clonogenic Assay | 0.21 ± 0.05 (n = 3) |
| HCC1806 (ER-) | CI (mean ± SD) |
| 4 μM SKI-II + 6.4 μM OSI-906 – Clonogenic Assay | 0.01 ± 0.01 (n = 2) |
Abbreviation: CI Combination Index
