Table 2.
SETBP1 mutations in juvenile myelomonocytic leukemia
| Reference | Number of Patients | Mutation Prevalence | Impact on Survival |
|---|---|---|---|
| [46] | 92 | 7 (7.6%) | Yes* (p-NR) |
| [47] | 42 | 2 (4.8%) | NR |
| [48] | 66 | 23 (24.8%) | No (p-0.258 – Univariate) Yes (p-0.026 – Multivariate) |
| [49] | 70 | 7 (10%) | Yes (p-0.03) |
NR Not reported; * Survival analysis was done in patients harboring SETBP1 or JAK3 mutations compared to patients without either mutation