Table 2.
Longitudinal model results for significant relationships of metabolic measures to regional D2/3R availability during VLCD.
| Caudate | Putamen | Ventral Striatum |
Substantia Nigra |
Hypothalamus | ||
|---|---|---|---|---|---|---|
| Leptin | Estimate | 0.12 | 0.12 | 0.08 | 0.01 | 0.01 |
| (95% C.I.) | (0.05,0.18) | (0.05,0.19) | (0.03, 0.12) | (0.007, 0.01) | (0.006,0.02) | |
| p-value | 0.001* | 0.002* | 0.004* | <0.001* | 0.001* | |
| Glucose | Estimate | 0.15 | 0.14 | 0.06 | 0.01 | 0.01 |
| (95% C.I.) | (0.02,0.27) | (0.006,0.28) | (−0.03,0.16) | (0.003,0.018) | (−0.003,0.03) | |
| p-value | 0.022 | 0.042 | 0.184 | 0.007* | 0.123 |
*
significant after correction for FDR