Table 3.
Outcomes of salvage treatments
| Author | Year | Modality | N | Followup (mo) |
Outcome | Grade 3–4 toxicity |
|---|---|---|---|---|---|---|
| Vaidya (23) | 2000 | RP | 6 | 27 | 83% 3-year FFP | 0% |
| Bianco (12) | 2005 | RP | 100 | 60 | 55% 5-year FFP | 13–33% |
| Izawa (24) | 2002 | Cryotherapy | 131 | 58 | 40% 5-year bNED | NR |
| Ismail (25) | 2007 | Cryotherapy | 100 | 34 | 59% 3-year bNED | NR |
| Bahn (26) | 2012 | Cryotherapy | 73 | 44 | 75% negative biopsy | |
| Grado (17) | 1999 | LDR | 49 | 64 | 34% 5-year bNED | 3% |
| Beyer (18) | 1999 | LDR | 17 | 62 | 53% 5-year FFP | 16% |
| Wong (27) | 2006 | LDR | 17 | 44 | 75% 4-year bNED | NR |
| Allen (28) | 2007 | LDR | 12 | 45 | 63% 4-year bNED | 47% |
| Nguyen (29) | 2007 | LDR | 25 | 47 | 70% 4-year bNED | 0% |
| Lee (30) | 2008 | LDR | 21 | 36 | 38% 5-year bNED | 30% |
| Aaronson (19) | 2009 | LDR | 24 | 30 | 88% 3-year bNED | 0% |
| Burri (20) | 2009 | LDR | 37 | 86 | 54% 10-year bNED | 11% |
| Chen (7) | 2013 | HDR | 52 | 60 | 51% 5-year bNED | 4% |
| Present series | 2013 | HDR | 42 | 38 | 70% 3-year bNED | 8% |
RP = radical prostatectomy; FFP = freedom from progression; bNED = biochemical non-evidence of disease; LDR = low-dose-rate brachytherapy; NR = not reported.