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. 2017 Dec 6;17:825. doi: 10.1186/s12885-017-3800-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — MTV was calculated by the thresholding method on FDG PET/CT. Focal activity in the uterine cervix was identified. A VOI was inserted manually, carefully avoiding the urinary bladder. SUVmax was quantified by the software automatically. The tumour was outlined as the region encompassed by a given fixed percent intensity level relative to the maximum activity in the tumour. 20% to 80% thresholds of the SUVmax (MTV₂₀ to MTV₈₀) at intervals of 5% were used in this study. MTV: metabolic tumour volume; VOI: volume of interest; SUVmax: maximum standardized uptake value