Supplemental Figure S3.

Correlates of cellular immune responses. A and B: Analysis of CD4⁺ central memory T (T_CM) cells found in whole blood throughout the study, demonstrating a modest decline after simian immunodeficiency virus (SIV) infection at week 9 (A), and the percentage of CD4⁺ T_CM cells proliferating as marked by Ki67⁺ (B). C: Example flow plots showing gating for (CD28⁺CD95^–)-naïve cells, (CD28⁺CD95⁺) T_CM cells, and (CD28⁻CD95⁺) effector memory T cells in CD4⁺ T cells. D and E: Analysis of CD8⁺ T_CM cells in whole blood (D), with percent CD8⁺ T_CM cells positive for Ki67 (E). F: Example flow plots showing gating for naïve cells, T_CM cells, and CD8⁺ effector memory T cells. Data are expressed as means ± SEM (A–D).