Table 4.

Pearson Correlations between Severity of Worst Tiredness and Other Instruments in RA-BEAM and RA-BUILD at Week 12

Instruments	Severity of Worst Tiredness
	RA-BEAM		RA-BUILD
	n	r	n	r
Week 12a
Duration of MJS	1281	0.32***	666	0.38***
Severity of MJS	1281	0.79***	666	0.77***
Severity of Worst Joint Pain	1281	0.82***	666	0.82***
SF-36
Role Physical Domain	1233	−0.45***	632	−0.42***
Bodily Pain Domain	1233	−0.51***	632	−0.52***
General Health Domain	1233	−0.39***	632	−0.38***
Social Functioning Domain	1233	−0.43***	632	−0.44***
Vitality Domain	1233	−0.52***	632	−0.51***
Role Emotional Domain	1233	−0.41***	632	−0.32***
Mental Health Domain	1233	−0.40***	632	−0.34***
Physical Functioning Domain	1233	−0.43***	632	−0.41***
Mental Component Score	1233	−0.40***	632	−0.34***
Physical Component Score	1233	−0.45***	632	−0.45***
FACIT-F Total Score	1233	−0.60***	632	−0.60***
HAQ-DI Total Score	1233	0.49***	632	0.46***
QIDS-SR16 Total Score	1231	0.37***	632	0.37***
Patient’s Assessment of Pain	1233	0.69***	632	0.65***
PtGA	1233	0.64***	632	0.62***
Tender Joint Count 28	1231	0.32***	630	0.40***
Swollen Joint Count 28	1231	0.21***	630	0.23***
PhGA	1224	0.35***	627	0.38***
hsCRP	1220	0.46***	623	0.49***

Abbreviations: FACIT-F = Functional Assessment of Chronic Illness Therapy-Fatigue; HAQ-DI = Health Assessment Questionnaire-Disability Index; hsCRP = high-sensitivity C-reactive protein; MJS = morning joint stiffness; n = number of patients; PtGA = Patient’s Global Assessment of Disease Activity; PhGA = Physician’s Global Assessment of Disease Activity; QIDS-SR₁₆ = Quick Inventory of Depressive Symptomatology Self-Rated-16; SF-36 = 36-Item Short Form Health Survey version 2 with Acute recall

Pearson correlation coefficients with significance using p-values denoted as: * ≤ 0.05, ** ≤ 0.01, *** ≤ 0.001

^aDaily average of seven days preceding visit that contained at least 4 measurements