. 2017 Dec 6;15:237. doi: 10.1186/s12955-017-0807-5

Table 7.

Known-Groups Validity of Severity of Worst Tiredness Using CDAI Subgroups at Week 4

PRO/Study	CDAI Category			p-value^a	Comparisons^b
PRO/Study	0.0 to ≤ 10.0 N, Mean (SD)	>10.0 to ≤ 22.0 N, Mean (SD)	>22.0 to ≤ 76.0 N, Mean (SD)	p-value^a	Comparisons^b
Severity of Worst Tiredness Week 4
RA-BEAM	220, 2.9 (2.0)	426, 4.2 (2.1)	567, 5.1 (2.0)	0.001	a: 0.001, b: 0.001, c: 0.001
RA-BUILD	134, 3.1 (2.0)	209, 4.1 (1.9)	275, 5.6 (2.0)	0.001	a: 0.001, b: 0.001, c: 0.001

Abbreviations: SD = standard deviation; CDAI = Clinical Disease Activity Index

^ap-value based on a comparison of mean values using ANOVA

^bNote for multiple comparison using Scheffé adjustment: a: 0.0 to ≤10.0 versus >10.0 to ≤22.0; b: 0.0 to ≤10.0 versus >22.0 to ≤76.0; c: >10.0 to ≤22.0 versus >22.0 to ≤76.0