Table 1.
Characteristics of the Patient Population.
| N (% < 250 ng/mL) | All Patients | T >=250 ng/dL | T <250 ng/dL | p-value | |
|---|---|---|---|---|---|
| Age (years) | 10,041 (15.1%) | 58 (48,68) | 58 (48,68) | 58 (48,69) | 0.2104 |
| BMI | 5,346 (14.9%) | 28 (25,32) | 27 (25,31) | 31 (27,36) | <.0001 |
| hsCRP (μU/mL) | 9,303 (14.9%) | 1.3 (0.9,3.0) | 1.2 (0.9,2.7) | 2.5 (1.1,5.6) | <.0001 |
| HDL (mg/dL) | 8,844 (14.8%) | 47 (39,58) | 48 (40,58) | 43 (35,52) | <.0001 |
| HbA1C (%) | 7,494 (15.0%) | 5.6 (5.4,5.9) | 5.6 (5.3,5.9) | 5.8 (5.5,6.4) | <.0001 |
| cTnI (pg/mL) | 10,041 (15.1%) | 1.2 (0.7,2.2) | 1.2 (0.7,2.2) | 1.3 (0.8,2.5) | <.0001 |
| IL-6 (pg/mL) | 10,041 (15.1%) | 1.4 (0.9,2.4) | 1.3 (0.8,2.2) | 2.0 (1.2,3.4) | <.0001 |
| IL-17A (pg/mL) | 10,041 (15.1%) | 0.4 (0.2,0.6) | 0.4 (0.2,0.6) | 0.4 (0.2,0.7) | <.0001 |
| TNF-α (pg/mL) | 10,041 (15.1%) | 2.5 (2.0,3.2) | 2.5 (1.9,3.2) | 2.7 (2.1,3.6) | <.0001 |
| ET-1 (pg/mL) | 2,836 (13.0%) | 2.5 (2.1,3.1) | 2.5 (2.1,3.0) | 2.5 (2.0,3.2) | 0.0584 |
| Leptin (ng/mL) | 9,216 (15.2%) | 7.1 (3.7,13.4) | 6.5 (3.4,11.8) | 13.1 (6.9,24.0) | <.0001 |
| NTproBNP (pg/mL) | 9,507 (15.1%) | 40 (18,97) | 39 (18,93) | 43 (18,124) | 0.0038 |
Data are represented as median value + interquartile range. P-values determined by Wilcoxon Rank Sum. cTnI, cardiac troponin I; ET-1, endothelin-1; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; IL-17A, interleukin-17A; NTproBNP, N-terminal pro-B-type natriuretic peptide; HDL, high-density lipoprotein, hsCRP, hs c-reactive protein; HbA1c, hemoglobin A1c.