Table 1. Characteristics of the family Hepeviridae.
Typical member: | human hepatitis E virus Burma (M73218), species Orthohepevirus A, genus Orthohepevirus |
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Virion | Non-enveloped, 27–34 nm diameter with a single capsid protein |
Genome | 6.4–7.2 kb capped positive-sense monopartite RNA containing three ORFs |
Replication | Occurs in association with the host endoplasmic reticulum |
Translation | From genomic (ORF1) and a subgenomic (ORF2 and ORF3) capped mRNA |
Host range | Mammals (Orthohepevirus A, C and D), birds (Orthohepevirus B) and trout (Piscihepevirus) |
Taxonomy | Two genera |