Table 2.
Comparison of baseline characteristics of 402 patients with kidney biopsies by development of ESRD during follow-up
| Variables | Non-ESRD, n=334 | ESRD, n=68 | P Value |
|---|---|---|---|
| Age, yr | 41 (31–50) | 43(31–51) | 0.51 |
| Women, % | 44 | 34 | 0.13 |
| Follow-up, mo | 35.8 (24.5–83.1) | 42.8 (27.1–63.8) | 0.94 |
| eGFR ml/min per 1.73 m2 | 91 (61–113) | 57 (34–83) | <0.001 |
| Systolic BP, mmHg | 129 (120–140) | 140 (125–150) | 0.11 |
| Urine protein, g/24 h | 1.9 (1.0–4.4) | 3.7 (2.4–5.6) | <0.001 |
| Serum albumin, g/dl | 3.5 (2.6–4.1) | 3.6 (2.7–3.9) | 0.91 |
| Urinary fibrinogen to Cr, ng/mg | 521.1 (177.5–1451.3) | 1599.9 (654.9–4148.6) | <0.001 |
| Global sclerosis, % | 8 (0–27) | 17 (33–58) | <0.001 |
| Segmental sclerosis, % | 0 (0–7) | 3 (0–14) | 0.01 |
| IFTA | 1 (1–2) | 2 (1–2) | <0.001 |
| Disease type, n (%) | <0.001 | ||
| IgAN | 130 (39) | 22 (32) | |
| IMN | 89 (27) | 5 (7) | |
| DN | 64 (19) | 37 (54) | |
| Focal segmental GN | 51 (15) | 4 (6) |
Cr, creatinine; IFTA, interstitial fibrosis and tubular atrophy; IgAN, IgA nephropathy; IMN, idiopathic membranous nephropathy; DN, diabetic nephropathy.