Table 2. Core genome multilocus sequence typing targets differing between the two ST345 outbreak variants identified in a 2013 Legionnaires’ disease outbreak, Germany.
| Targeta | Begin | End | Gene name | GenBank protein_ID | cgMLST allele number ST345-A |
cgMLST allele number ST345-B |
SNPs per target |
|---|---|---|---|---|---|---|---|
| Differing cgMLST targets in 42 kb recombination region (27 targets) | |||||||
| lpg2604 | 2938631 | 2939434 | NAb | YP_096609.1 | 1 | 4 | 11 |
| lpg2606 | 2940021 | 2940887 | NAb | YP_096611.1 | 1 | 4 | 5 |
| lpg2607 | 2941026 | 2943062 | pepO | YP_096612.1 | 1 | 4 | 21 |
| lpg2608 | 2943206 | 2944120 | lpxC | YP_096613.1 | 1 | 2 | 9 |
| lpg2609 | 2944368 | 2945564 | ftsZ | YP_096614.1 | 1 | 4 | 12 |
| lpg2610 | 2945759 | 2947021 | ftsA | YP_096615.1 | 1 | 4 | 26 |
| lpg2612 | 2947732 | 2948838 | ddl | YP_096617.1 | 1 | 4 | 16 |
| lpg2614 | 2949745 | 2951154 | murC | YP_096619.1 | 1 | 4 | 17 |
| lpg2615 | 2951164 | 2952348 | ftsW | YP_096620.1 | 3 | 5 | 14 |
| lpg2616 | 2952345 | 2953688 | murD | YP_096621.1 | 1 | 4 | 9 |
| lpg2617 | 2953702 | 2954820 | mraY | YP_096622.1 | 1 | 4 | 7 |
| lpg2618 | 2954902 | 2956287 | murF | YP_096623.1 | 1 | 4 | 13 |
| lpg2619 | 2956480 | 2957259 | NAb | YP_096624.1 | 1 | 4 | 7 |
| lpg2620 | 2957264 | 2960758 | NAb | YP_096625.1 | 1 | 5 | 63 |
| lpg2621 | 2960933 | 2961613 | NAb | YP_096626.1 | 1 | 4 | 9 |
| lpg2622 | 2961715 | 2962776 | NAb | YP_096627.1 | 1 | 4 | 13 |
| lpg2623 | 2963086 | 2963898 | NAb | YP_096628.1 | 1 | 4 | 12 |
| lpg2624 | 2963973 | 2964455 | greA | YP_096629.1 | 1 | 4 | 10 |
| lpg2625 | 2964464 | 2967667 | carB | YP_096630.1 | 1 | 4 | 77 |
| lpg2626 | 2967794 | 2968066 | NAb | YP_096631.1 | 1 | 4 | 22 |
| lpg2627 | 2968179 | 2969360 | NAb | YP_096632.1 | 1 | 4 | 85 |
| lpg2629 | 2970147 | 2971217 | NAb | YP_096634.1 | 1 | 4 | 13 |
| lpg2630 | 2971214 | 2972215 | NAb | YP_096635.1 | 1 | 4 | 15 |
| lpg2631 | 2972463 | 2973947 | pepA | YP_096636.1 | 1 | 4 | 25 |
| lpg2633 | 2974501 | 2974818 | NAb | YP_096638.1 | 3 | 5 | 5 |
| lpg2635 | 2976210 | 2977781 | mviN | YP_096640.1 | 1 | 4 | 26 |
| lpg2636 | 2978139 | 2978405 | rpsT | YP_096641.1 | 1 | 2 | 2 |
| Differing cgMLST targets of 26 kb recombination region (13 targets) | |||||||
| lpg2666 | 3013221 | 3014102 | NAb | YP_096671.1 | 1 | 4 | 9 |
| lpg2667 | 3014236 | 3015114 | rpoH | YP_096672.1 | 1 | 4 | 5 |
| lpg2668 | 3015387 | 3016316 | ftsX | YP_096673.1 | 1 | 4 | 15 |
| lpg2671 | 3018077 | 3019402 | NAb | YP_096676.1 | 1 | 4 | 17 |
| lpg2672 | 3019399 | 3020703 | NAb | YP_096677.1 | 1 | 4 | 25 |
| lpg2673 | 3020700 | 3021245 | NAb | YP_096678.1 | 1 | 4 | 10 |
| lpg2676 | 3022673 | 3023836 | dotB | YP_096681.1 | 1 | 4 | 21 |
| lpg2678 | 3025688 | 3026485 | NAb | YP_096683.1 | 1 | 4 | 4 |
| lpg2679 | 3026515 | 3027459 | NAb | YP_096684.1 | 1 | 4 | 17 |
| lpg2680 | 3027690 | 3028718 | murE3 | YP_096685.1 | 1 | 4 | 27 |
| lpg2683 | 3030713 | 3032560 | NAb | YP_096688.1 | 1 | 4 | 118 |
| lpg2684 | 3032560 | 3033420 | NAb | YP_096689.1 | 3 | 5 | 35 |
| lpg2687 | 3037576 | 3038031 | icmV | YP_096692.1 | 1 | 4 | 34 |
cgMLST: core genome multilocus sequence typing; ID: identity; SNP: single nt polymorphism; NA: not applicable.
a Reference genome Legionella pneumophila strain Philadelphia-1; GenBank accession number NC_002942.5; cgMLST allele number for each target: ‘1’.
b There is currently no assigned name for this gene.