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. 2017 Dec 6;11(12):e0006091. doi: 10.1371/journal.pntd.0006091

Table 4. Multivariate stepwise logistic regression analysis for mortality (N = 22, 767).

Variables Univariate logistic regression analysis Multivariate stepwise logistic regression analysis
OR (95% CI) p OR (95% CI) p
Age 1.12 (1.10–1.13) 0.0001 1.11 (1.10–1.12) 0.0001
Gender 0.441 0.19
 Female reference reference
 Male 1.12 (0.84–1.51) 1.23 (0.91–1.66)
The levels of hospitals/clinics reporting dengue cases
 Medical center reference reference
 Regional hospital 0.61 (0.45–0.83) 0.002 0.68 (0.49–0.94) 0.018
 District hospital 0.39 (0.10–1.57) 0.182 1.03 (0.24–4.46) 0.965
 Clinics 0.12 (0.05–0.27) 0.0001 0.27 (0.12–0.62) 0.002
 Other 0.11 (0.02–0.76) 0.025 0.33 (0.05–2.4) 0.274
Respiratory distress 30.12 (15.39–58.93) 0.0001 9.66 (4.57–20.44) 0.0001
Altered consciousness 34.40 (11.30–104.68) 0.0001 7.06 (2.19–22.73) 0.001
Thrombocytopenia 4.04 (2.05–7.98) 0.0001 2.55 (1.24–5.28) 0.011
Myalgia 0.27 (0.16–0.45) 0.0001 0.39 (0.23–0.66) 0.0001
Bone and joint pain 0.32 (0.14–0.73) 0.007 0.52 (0.23–1.19) 0.119
Abnormal heart rhythm 15.86 (1.97–127.44) 0.009
Shock 15.03 (4.78–53.71) 0.0001
Chest tightness/ pain 7.97 (1.89–33.49) 0.005
Bleeding 3.72 (1.36–10.16) 0.010
Fatigue 2.18 (1.23–3.85) 0.007
Fever 0.50 (0.32–0.73) 0.002
Skin rash 0.42 (0.20–0.89) 0.024
Headache 0.39 (0.24–0.63) 0.0001

Variables entered on step 1 of the multivariate stepwise logistic regression analysis: All variables with p ≤ 0.05 in the univariate logistic regression analysis.