Table 2. Conformational alterations in the lengths of LPAR6 extra and intra cellular segments upon conotoxins binding at 20ns interval.

IC and EC denote intracellular and extracellular regions, respectively.

	IC1	EC1	IC2	EC2	IC3	EC3
Apo-LPAR6	Ile41- Tyr55	Phe75- Asp86	Ile110- Val136	Ser66- Thr179	Cys203- Ile231	Tyr250- Tyr271
LPAR6-contryphan-R	Cys44- Tyr53	Pro71- Lys90	Asp113- Asn132	Pro150- Ile184	Val207- Leu228	Leu249- Tyr276
LPAR6-BuIA	Cys44- Glu51	Pro70- Met94	Arg114- Arg131	Ala149- Val185	Met206- Lys229	Asn248- Ile275
LPAR6-contryphan-Lo	Val45- Tyr52	Pro71-Val93	Asp113- Arg131	Ala149- Arg183	Val207- Leu228	Asn248- Leu277