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. 2017 Dec 6;12(12):e0178918. doi: 10.1371/journal.pone.0178918

Table 4. Intervention, NHS healthcare and societal costs (£) over 12 month follow-up between intervention groups: Complete case analysis.

Acupuncture Alexander lessons Usual care
(n = 104) (n = 89) (n = 100)
Intervention costs
Mean (95% CI) 389.38 (372.68–406.07) 586.96 (549.08–624.83)** -
Min-max [0–420] [0–660]
Healthcare resource use costs
Mean (95% CI) 558.01 (412.73–703.28) 612.72 (415.27–810.17) 484.27 (370.78–597.75)
Private healthcare for neck pain
Mean (95% CI) 85.13 (51.46–118.79) 69.16 (22.19–116.13) 60.25 (28.00–92.51)
Lost productivity costsa
Mean (95% CI) 185.61 (74.46–296.75) 465.27 (61.95–868.58) 176.34 (50.39–302.29)
Total NHS healthcare costs
Mean (95% CI) 947.38 (800.43–1094.33)** 1199.68 (999.84–1399.51)** 484.27 (370.78–597.75)
Incremental NHS healthcare costsb
Unadjusted difference 463.12 715.41 -
Adjusted difference (bootstrapped 95% CI)c 451.32 (285.29 to 634.83) 667.24 (472.28 to 896.42)
Total societal costs
Mean (95% CI) 1218.11 (1036.85–1399.38)** 1734.10 (1268.44–2199.76)** 720.86 (530.61–911.10)
Incremental societal costsb
Unadjusted difference 497.25 1013.24 -
Adjusted difference (bootstrapped 95% CI)d 509.44 (252.11 to 775.93) 861.70 (491.52 to 1286.13)

**p<0.001 (independent samples t-test comparing means for acupuncture vs. usual care and Alexander vs. usual care, or acupuncture vs. Alexander for intervention costs)

aIncludes time off work due to neck pain and time off work to attend intervention sessions

bIncremental costs calculated as mean costs of acupuncture group minus mean costs of usual care group and mean costs of Alexander group minus mean costs of usual care group.

cAdjusted for baseline NHS healthcare costs and practice size. 95% non-parametric bias-corrected confidence intervals based on 1,000 bootstrap replications.

dAdjusted for baseline NHS societal costs and practice size. 95% non-parametric bias-corrected confidence intervals based on 1,000 bootstrap replications.