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. 2017 Sep 22;13(12):2967–2976. doi: 10.1080/21645515.2017.1368598

Table 1.

Histopathological lesion score of the lungs from vaccinated mice.

Saline Infection BCG Advax4 Advax4+CMX Advax4+ECMX
0 +++ + ++ +++ +
0 +++ ++ ++ +++ +
0 +++ + ++ +++ ++

Histopathologic scoring of lung infiltration in challenged and vaccinated mice. Scoring of the lesion was determined as: absence of inflammatory infiltrate: zero; mild inflammatory infiltrate (until 25% of the lung): +; moderate inflammatory infiltrate (until 50% of the lung): ++; strong infiltrate (more than 50% of the lung): +++. Three different areas of the histopathological slides from each group were evaluated.