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Effect of MK2206 treatment on tumor volume. PDX tumors were grafted under the renal capsule of NSG mice. Mice were treated with either vehicle control or 120mg/kg twice a week with MK2206 for 3 weeks. Tumors were (A) visualized and (B) measured. Tumors from USC1, EEC2 and EEC4 are shown (* denotes statistical significance, p < 0.05).
