. 2017 Jun 12;13(12):2837–2848. doi: 10.1080/21645515.2017.1330236

Table 1.

Molecular adjuvants tested in vivo.

Molecular Adjuvant	Molecule Type	Animal Model	Adaptive Response Effect	References
CD40L	Co-Stimulatory	Mice	Cellular	¹⁶¹
CD80/86	Co-Stimulatory	Mice, NHP	Cellular	¹⁶²
GM-CSF	Cytokine	Mice	Humoral	¹⁶³
ICAM-1	Co-Stimulatory	Mice	Cellular	¹⁶⁴
IFN-γ	Cytokine	Mice, NHP	Cellular	¹⁶⁵
IL-2	Cytokine	Mice	Cellular, Humoral	^165,166
IL-4	Cytokine	Mice, NHP	Humoral	^166,167
IL-7	Cytokine	Mice	Cellular, Humoral	¹⁶⁸
IL-8	Chemokine	Mice	Cellular, Humoral	^169,170
IL-10	Cytokine	Mice	Cellular	¹⁶⁶
IL-12	Cytokine	Mice, NHP	Cellular	^98,171
IL-15	Cytokine	Mice, NHP	Cytokine	^98,172
IL-18	Cytokine	Mice, NHP	Cytokine	^166,173
MCP-1	Chemokine	Mice	Humoral	¹⁶⁹
M-CSF	Cytokine	Mice	Cellular	¹⁶³
MIP-1α	Chemokine	Mice	Humoral	¹⁶⁹
RANTES	Chemokine	Mice	Cellular	^{169, 170}