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. 2017 Sep 21;13(12):2996–3009. doi: 10.1080/21645515.2017.1380137

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© 2017 The Author(s). Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 7. — Neutralizing activity in rabbit sera elicited by ether DP6-001 and new polyvalent formulation. (A) Percent of inhibition by rabbit immune sera in the PhenoSense assay. Each curve represent serum from one rabbit. (B) Neutralizing titers in rabbit immune sera as tested by TZM-bl assays. Five rabbit sera were tested for each formulation. The mean titers with standard deviations are shown. NAb titer is defined as the serum dilution capable of inhibiting 50% of viral infection. Rabbit sera collected two weeks after the final boost immunization were tested for their ability to neutralize various viruses. The statistical significance (p < 0.05) is indicated with “*”, using one way ANOVA.