Skip to main content
. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Reprod Toxicol. 2017 Sep 29;74:150–157. doi: 10.1016/j.reprotox.2017.09.013

Figure 7. Effect of BPA and DES on Steroidogenic Enzyme mRNA Levels in the F2 generation (12 months).

Figure 7

Ovaries were collected from the F2 generation of mice at 12 months of age, and then subjected to quantitative polymerase chain reaction for Star (panel A), Cyp11a1 (panel B), Hsd3b1 (panel C), Hsd17b1 (panel D), and Cyp19a1 (panel E). The graph represents the means ± SEM (n = 3–9 ovaries/treatment) of relative fold changes normalized to Actb. Asterisks (*) represent statistically significant differences from the vehicle control (p ≤ 0.05). ^ indicates p = 0.09 for DES versus control (panel A), p = 0.07 for DES versus control (panel B), p = 0.11 for BPA 50 µg/kg versus control (panel B), p = 0.06 for DES versus control (panel D), and p = 0.07 for BPA 50 µg/kg versus control (panel D).