Skip to main content
. Author manuscript; available in PMC: 2018 Dec 5.
Published in final edited form as: Cell Metab. 2017 Oct 26;26(6):872–883.e5. doi: 10.1016/j.cmet.2017.09.023

Figure 7. Impaired proteostasis and altered mitophagy in Mfn1/Mfn2/Drp1 TKO mouse hearts.

Figure 7

(A) Induction of the mitochondrial unfolded protein response. Samples are myocardial homogenates; GAPDH is loading control. * is p<0.05 vs Ctrl (ANOVA).

(B) Mitophagy proteins in cardiac mitochondrial fractions. TOM20 is loading control. * is p<0.05 vs Ctrl; # is p<0.05 vs Drp1 KO (ANOVA).

(C) Macroautophagy proteins in myocardial homogenates. GAPDH is loading control. * is p<0.05 vs Ctrl (ANOVA). Bottom GAPDH is loading control for LC3 blots. See also Figures S4 and S5.