Table 1. Baseline characteristics of study subjects by HIV status.
Results are displayed as median (IQR) or percentage. HOMA-IR, homeostatic model of insulin resistance; GFR, glomerular filtration rate; LDL, low-density lipoprotein cholesterol concentration; HDL, high-density lipoprotein cholesterol concentration.
| HIV+ (n=55) | HIV-negative (n=19) | |
|---|---|---|
| Age (years) | 49 (43–55) | 50 (34–56) |
| Male gender | 84% | 74% |
| African American | 73% | 47% |
| Current smoker | 55% | 53% |
| Packs per day | 0.5 (0.2–1) | 1 (0.5–1) |
| Body mass index (kg/m2) | 26 (23–31) | 27 (26–30) |
| Diabetes | 1.8% | 0% |
| HOMA-IR | 3.1 (1.6–4.8) | 2.1 (1.8–3.8) |
| Hypertension | 56% | 16% |
| Estimated GFR (mL/min/1.73m2) | 88 (76–102) | 84 (73–107) |
| LDL cholesterol (mg/dL) | 87 (70–114) | 88 (76–116) |
| HDL cholesterol (mg/dL) | 47 (37–60) | 45 (35–58) |
| Statin use | 11% | 5% |
| Coronary artery calcium >0 | 43% | 39% |
| CD4+ T-cell count (cells/μl) | 690 (443–818) | N/A |
| Nadir CD4+ T-cells (cells/μl) | 189 (46–303) | N/A |
| HIV-1 RNA <20 copies/ml | 88% | N/A |
| Current protease inhibitor | 43% | N/A |
| Current abacavir | 7% | N/A |