Table 1.
Demographic and physiological data.
| Characteristic | Neither (N=130) |
HS Only (N=388) |
TBI Only (N=28) |
HS and TBI (N-124) |
All (N=670) |
|---|---|---|---|---|---|
|
| |||||
| Age in years | 37.5 (27,51) | 32 (24, 46.5) | 55 (38, 69.5) | 35.5 (23,56) | 34.5 (25,51) |
|
| |||||
| Treatment Group (%) | |||||
| 1:1:1 | 67 (51.5) | 197 (50.8) | 20 (71.4) | 51 (41.1) | 335 (50) |
| 1:1:2 | 63 (48.5) | 191 (49.2) | 8 (28.6) | 73 (58.9) | 225 (50) |
|
| |||||
| Gender (%) | |||||
| Male | 111 (85.4) | 318 (82.0) | 18 (64.3) | 90 (72. 6) | 537 (80.1) |
| Female | 19 (14.6) | 70 (18.0) | 10 (35.7) | 34 (27.4) | 133 (19.9) |
|
| |||||
| Race (%) | |||||
| Caucasian | 73 (56.2) | 237 (61.1) | 22 (78.6) | 102 (82.3) | 434 (64.8) |
| African American | 49 (37.7) | 114 (29.4) | 1 (3.6) | 14 (11.3) | 178 (26.6) |
| Other Race | 9 6.9) | 37 (9.5) | 5 17.9) | 8 (6.5) | 59 (8.8) |
|
| |||||
| Mechanism of Injury | |||||
| Blunt injury only | 55 (42.3) | 164 (42.3) | 27 (96.4) | 104 (83.9) | 357 (53.3) |
| Penetrating injury only | 75 (57.7) | 220 (56.7) | 1 (3.6) | 17 (13.7) | 320 (47.8) |
| Both types of injury | 0 | 5 (1.0) | 0 | 3 (2.4) | |
|
| |||||
| Systolic blood pressure | 114 (88, 132) | 100 (80,124) | 104 (82, 131) | 98 (79,123) | 102 (80,126) |
|
| |||||
| Heart rate | 99 (82,120) | 118 (98,133) | 104 (80, 122) | 120 (98,142) | 114 (94,132) |
|
| |||||
| Respiratory rate | 20 (16,26) | 22 (18,28) | 20 (16.5,22) | 20 (16,24) | 20 (17,26) |
|
| |||||
| Glasgow Coma Scale | 15 (13,15) | 14 (5.5,15) | 3 (3,11.5) | 3 (3,8) | 14 (3,15) |
|
| |||||
| Head AIS scores | 0 | 0 | 5 (2.5,5) | 4 (3,5) | 0 (0,2) |
|
| |||||
| Prehospital intubation (%) | 20 (15.4) | 74 (19.1) | 13 (46.4) | 72 (58.1) | 179 (26.7) |
|
| |||||
| pH (median, IQR) | 7.3 (7.3, 7.4) | 7.2 (7.1,7.3) | 7.3 (7.3,7.4) | 7.2 (7.0,7.3) | 7.2 (7.1,7.3) |
|
| |||||
| Base excess | −1.5 (−3,1.1) | −10 (−14.3, −6.8) | −1 (−2.4,1.2) | −10.4 (−14, −7.6) | −8 (−12.7, −4) |
|
| |||||
| Lactate | 3.4 (2.5, 5.1) | 7 (4.7, 10.7) | 3.3 (2.3, 4.0) | 6.3 (4.7,9.2) | 6 (3.7, 9.2) |
|
| |||||
| Hematocrit | 37 (33.2, 41.6) | 34.7 (29.1, 39.4) | 34.2 (28.5, 40.8) | 34.1 (30.5, 38.6) | 35 (30.4, 39.5) |
|
| |||||
| PT | 14.8 (13.9, 16.1) | 15.6 (14.4, 17.3) | 15.3 (14.9, 17) | 17.6 (15.7, 20.2) | 15.7 (14.5, 17.6) |
|
| |||||
| aPTT | 27 (24, 30.3) | 28.6 (25.4, 33.8) | 32 (29,40) | 38.9 (30.4, 53) | 29.6 (25.5, 35.5) |
|
| |||||
| INR | 1.2 (1.1,1.3) | 1.3 (1.2, 1.5) | 1.3 (1.2, 1.6) | 1.5 (1.3, 1.7) | 1.3 (1.2, 1.5) |
|
| |||||
| Thromboelastography results* | |||||
|
| |||||
| R-time (minutes) | 3.3 (2.7,4.2) | 3.8 (2.8,4.7) | 3.6 (3,4.4) | 4.2 (3.2,5) | 3.8 (2.9,4.7) |
|
| |||||
| K-time (minutes) | 1.3 (1.1,1.7) | 1.4 (1.2,1.8) | 1.4 (1.2,2.2) | 1.8 (1.3,2.5) | 1.5 (1.2,1.9) |
|
| |||||
| Alpha angle (%) | 72.4 (67.4,75.3) | 70.7 (65.7,74.3) | 68.3 (61.3,73.4) | 65.1 (59,70.4) | 70.2 (64.2,74.3) |
|
| |||||
| Maximum amplitude (mm) | 61.2 (56,65.4) | 61.5 (55.4,66) | 61.2 (57.8,66.8) | 57.3 (46.3, 63.1) | 60.8 (54.2, 65.4) |
|
| |||||
| G-value (d/sc) | 7.9 (6.4, 9.5) | 8 (6.3, 9.7) | 7.9 (6.8, 10) | 6.7 (4.3, 8.6) | 7.8 (5.9, 9.4) |
|
| |||||
| Ly30 (%) | 0.6 (0, 1.9) | 0.3 (0, 1.9) | 0.1 (0,1) | 0.7 (0, 8) | 0.3 (0, 2.2) |
*
Thromboelastography data were not available for all patients. Data are presented as medians with an interquartile range (P25,P75).