Table 3.

Parameters at time of euthanasia of moribund animals or at study conclusion.

Variable	FFP (n=14)		NS (n=14)		p-value†
	Survived to 48h (n=8, 57%)	Died before 48h (n=4, 29%)*	Survived to 48h (n=2, 14%)	Died before 48h (n=12, 86%)
Weight (g)	363 ± 20	361 ± 42	349 ± 20	399 ± 33	0.05
Sodium (mEq/L)	144 ± 2	147 ± 4	142 ± 6	145 ± 3	0.28
Potassium (mEq/L)	3.8 ± 0.4	7.6 ± 3.7	4.8 ± 1.5	9.9 ± 3.4	<0.01
Chloride (mEq/L)	97 ± 2	94 ± 3	99 ± 6	96 ± 4	0.35
Bicarbonate (mEq/L)	23 ± 6	21 ± 2	24 ± 5	20 ± 3	0.57
BUN (mg/dL)	27 ± 18	94 ± 7	22 ± 2	84 ± 16	<0.01
Creatinine (mg/dL)	0.8 ± 0.4	2.0 ± 0.6	1.2 ± 0.1	2.0 ± 0.5	<0.01
Lactate (mEq/L)	2.0 ± 0.5	5.3 ± 2.3	2.6 ± 0.1	4.9 ± 2.1	<0.01
Hematocrit	35 ± 3	35 ± 5	30 ± 1	36 ± 4	0.22
pH‡	7.27 ± 0.03	6.9 ± 0.22	7.24 ± 0.21	6.77 ± 0.13	<0.01
PCO2 (mmHg)‡	49 ± 13	101 ± 50	55 ± 16	145 ± 43	<0.01
PO2 (mmHg)‡	80 ± 76	41 ± 20	100 ± 113	36 ± 17	0.17
Base excess (mEq/L)‡	−4.5 ± 5.6	−11.8 ± 4.8	−3.8 F± 8.3	−14.0 ± 3.9	<0.01

^*In two FFP animals, a terminal blood sample was not obtained prior to animal death.

^†One-way analysis of variance for four groups. For all p<0.05, post-hoc tests demonstrated differences only between surviving and deceased groups.

^‡Mixed venous blood gas from cardiac puncture under 99% FiO2