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Membrane activities (expressed as EC50) of CPPs and CPP/pDNA complexes and stabilities against proteinase K treatment (expressed as t1/2).
| Peptide | EC50 (μM) of CPP | EC50 (μM) of CPP/pDNA | Proteinase K: t1/2 (min) of the complexed pDNA (95%CI) |
|---|---|---|---|
| PF14 | 0.66 | 1.43 | 108.3 (101.9 ± 118.4) |
| PF14-O | 0.60 | 1.17 | 94.2 (90.7 ± 97.4) |
| PF14-E | 0.67 | 2.36 | 16.7 (10.5 ± 21.8) |
| C0-PF14 | 5.36 | 7.09 | 0.5 (−0.8 ± 1.5) |
| C10-PF14 | 0.36 | 0.86 | 26.7 (20.1 ± 32.5) |
| C22-PF14 | 0.64 | 1.47 | 162.7 (159.6 ± 166.7) |
| PF6 | 0.96 | 1.80 | N/A |
