Figure 4.

Multiple sequence alignment of CK2α with the other CMGC kinases, CDK, CDKL, GSK, CLK and MAPK. The sequences were aligned using the ClustalX method. The figure was created with ESpript. The sequence of 30-110 of CK2α is shown. Residues with a conservation of greater than 70% are color-coded. Mutations are indicated at the corresponding positions. Residues that were not conserved (V31, W33, P72, V73, K74, K75, I78, K102, R107, T108 and P109) are shown in gray. A red character with a blue color scheme indicates similarity in a group (I82), and a red box with a white character indicates strict identity.