Table 1. The predicted allosteric sites in the CK2α proteins.
Rank | Representative residues | Feature score | Perturbation score | Allosite score |
---|---|---|---|---|
Site 1 | F113, E114, N118, D120 | 0.985 | 0.649 | 0.918 |
Site 2 | L249, W281, Y307 | 0.610 | 0.131 | 0.514 |
Site 3 | M225, Y125, L128 | 0.967 | 0.155 | 0.805 |
Site 4 | Y211, H148, T314 | 0.820 | 0.165 | 0.689 |
Site 5 | W33, K75, I78, P109 | 0.819 | 0.209 | 0.697 |
Site 6 | Y39, V67, V112, V101 | 0.573 | 0.310 | 0.520 |