Table 1.
Effect of decreased PRDX activity on sperm motility and motion kinematics.
| Parameter | Control | Conoidin A | ||
|---|---|---|---|---|
| 1 μM | 10 μM | 100 μM | ||
| MOT (%) | 72.52 ± 1.22a | 71.16 ± 1.33a | 61.56 ± 0.35b | 37.94 ± 1.71c |
| HYP (%) | 20.52 ± 2.49a | 17.63 ± 3.1a,b | 19.43 ± 3.91a,b | 6.97 ± 1.7b |
| VCL (μm/s) | 149.03 ± 4.44a | 145.82 ± 5.12a | 149.33 ± 7.41a | 110.66 ± 0.98b |
| VSL (μm/s) | 56.99 ± 2.27a | 57.79 ± 1.92a | 59.95 ± 4.47a | 33.31 ± 2.23b |
| VAP (μm/s) | 66.56 ± 2.66a | 67.07 ± 2.56a | 67.85 ± 3.54a | 43.71 ± 1.29b |
| ALH (μm) | 6.27 ± 0.2a | 5.99 ± 0.2a | 6.12 ± 0.28a | 4.54 ± 0.1b |
| LIN (%) | 38.36 ± 0.76a | 39.68 ± 1.12a | 39.95 ± 0.96a | 30.21 ± 1.92b |
| WOB (%) | 44.65 ± 0.46a | 46.04 ± 1.32a | 45.36 ± 0.26a | 39.62 ± 0.7b |
Data presented as mean ± SEM, n = 3. MOT = motility (%), HYP = hyperactivated motility; VCL = curvilinear velocity (µm/s), VSL = straight-line velocity (µm/s), VAP = average path velocity (µm/s), ALH = mean amplitude of head lateral displacement (µm), LIN (%) = linearity, and WOB (%) = wobble. Superscripts (a,b,c) within the same row indicate significant differences (P < 0.05).