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. 2017 Dec 7;7:17114. doi: 10.1038/s41598-017-16788-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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RNA-seq data analysis of BMs, AMs, and TMs. (A) Heatmap of hierarchical clustering indicate differentially expressed genes (rows) between BMs, AMs, and four samples of TMs. (fold-change > 2, P < 0.05). Red indicates up-regulation and green indicates down-regulation. (B) Dendrogram of hierarchical clustering indicates the interclass correlation between the three MSC groups. (C) The differentially expressed genes between AMs, BMs, and TMs are shown as up-regulated or down-regulated.