Table 1.
Antibodies used in the study.
| Antibody | Immunogen | Host | Application | Source | Catalog Number |
|---|---|---|---|---|---|
| 4G8 | aa 18-22 of human beta amyloid (VFFAE) | Mouse | IHC | Covance | SIG-39220 |
| APP | aa 66-81 of APP {N-terminus} | Mouse | WB | Millipore | MAB348 |
| BACE1 | aa human BACE (CLRQQHDDFADDISLLK) | Rabbit | WB | IBL | 18711 |
| ADAM10 | aa 732-748 of human ADAM 10 | Rabbit | WB | Millipore | AB19026 |
| PS1 | aa around valine 293 of human presenilin 1 | Rabbit | WB | Cell Signaling | 3622 S |
| Nicastrin | aa carboxy-terminus of human Nicastrin | Rabbit | WB | Cell Signaling | 3632 |
| APH1 | Synthetic peptide from hAPH-1a | Rabbit | WB | Millipore | AB9214 |
| Pen2 | aa N-terminal of human and mouse Pen-2 | Rabbit | WB | Invitrogen | 36-7100 |
| HT7 | aa 159-163 of human tau | Mouse | WB | Thermo | MN1000 |
| AT8 | Peptide containing phospho-S202/T205 | Mouse | WB | Thermo | MN1020 |
| AT180 | Peptide containing phospho-T231/S235 | Mouse | WB | Thermo | P10636 |
| AT270 | Peptide containing phospho-T181 | Mouse | WB | Thermo Scientific | MN1050 |
| PSD95 | Purified recombinant rat PSD-95 | Mouse | WB, IHC | Thermo | MA1-045 |
| SYP | aa 221-313 of SYP of human origin | Mouse | WB | Santa Cruz | sc-55507 |
| IBA1 | Linear peptide corresponding to human IBA1 | Mouse | WB | Millipore | MABN92 |
| GFAP | spinal chord homogenate of bovine origin | Mouse | WB | Santa Cruz | sc-33673 |
| Atg5/12 | KLH-conjugated linear peptide corresponding to human ATG5 | Rabbit | WB | Millipore | ABC14 |
| Atg7 | Synthetic peptide corresponding to N-term of ATG7 | Rabbit | WB | Cell Signaling | 2631 |
| LC3BI/II | Synthetic peptide corresponding to N-term of LC3B | Rabbit | WB | Cell Signaling | 2775 |
| CD10 | aa 230-550 mapping within an internal region of CD10 of human origin | Rabbit | WB | Santa Cruz | sc-9149 |
| IDE | Synthetic peptide corresponding to N-term of human IDE | Goat | WB | Santa Cruz | sc-27265 |
| ApoE | 19-311 mapping at the C-terminus of apoE of mouse origin | Rabbit | WB | Santa Cruz | sc-98574 |
| CREB | Synthetic peptide corresponding to N-term of human CREB | Rabbit | WB | Cell Signaling | 9197 |
| pCREB | Synthetic peptide corresponding to the residues surrounding Ser133 of CREB | Rabbit | WB | Cell Signaling | 9198 |
| c-Fos | Peptide mapping the internal region of human c-Fos | Rabbit | WB | Santa Cruz | sc-253 |
| BDNF | Peptide mapping the internal region of human BDNF | Rabbit | WB | Santa Cruz | sc-456 |
| Actin | gizzard Actin of avian origin | Mouse | WB | Santa Cruz | sc-47778 |
WB: Western blot; IHC: immunohistochemistry.